AHCYL2 Gene Summary [Human]
The protein encoded by this gene acts as a homotetramer and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Details
| Type | Protein Coding |
| Official Symbol | AHCYL2 |
| Official Name | adenosylhomocysteinase like 2 [Source:HGNC Symbol;Acc:HGNC:22204] |
| Ensembl ID | ENSG00000158467 |
| Bio databases IDs | |
| Aliases | adenosylhomocysteinase like 2 |
| Synonyms | 4631427C17Rik, adenosylhomocysteinase-like 2, ADOHCYASE3, IRBIT2, KIAA0828, mKIAA0828, RGD1564895, S-adenosylhomocysteine hydrolase-like 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human AHCYL2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rossmann-fold NAD(P)(+)-binding proteins
- S-adenosyl-L-homocysteine hydrolase, NAD binding domain
- S-adenosyl-L-homocysteine hydrolase
- adenosylhomocysteinase
- TrkA-N domain
- enzyme
- protein binding
Pathways
Biological processes and signaling networks where the AHCYL2 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- intracellular membrane-bounded organelle
- cytosol
- neurites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human AHCYL2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- S-adenosylmethionine cycle
- one-carbon metabolic process
Cellular Component
Where in the cell the gene product is active
- cytosol
- endoplasmic reticulum
- neuron projection
Molecular Function
What the gene product does at the molecular level
- protein binding
- adenosylhomocysteinase activity