ZDHHC23 Gene Summary [Human]
Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in protein localization to plasma membrane and protein palmitoylation. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZDHHC23 |
| Official Name | zinc finger DHHC-type palmitoyltransferase 23 [Source:HGNC Symbol;Acc:HGNC:28654] |
| Ensembl ID | ENSG00000184307 |
| Bio databases IDs | |
| Aliases | zinc finger DHHC-type palmitoyltransferase 23 |
| Synonyms | DHHC-23, Gm1751, Gm779, LOC100911213, NIDD, zinc finger, DHHC domain containing 23, zinc finger DHHC-type palmitoyltransferase 23 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZDHHC23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DHHC palmitoyltransferase
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Crohn disease
- lung adenocarcinoma formation
- lung adenocarcinoma
- psoriasis
role in cell
- palmitoylation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZDHHC23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-L-cysteine S-palmitoylation
- protein palmitoylation
- protein targeting to membrane
- protein localization in plasma membrane
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein-cysteine S-palmitoleyltransferase activity
- protein binding