ZFP1 Gene Summary [Human]
This gene belongs to the zinc finger protein family. Some members of this family bind to DNA by zinc-mediated secondary structures called zinc fingers, and are involved in transcriptional regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Details
| Type | Protein Coding |
| Official Symbol | ZFP1 |
| Official Name | ZFP1 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:23328] |
| Ensembl ID | ENSG00000184517 |
| Bio databases IDs | |
| Aliases | ZFP1 zinc finger protein |
| Synonyms | Fnp-1, IMAGE:5043236, mkr-1, RGD1565049, ZFP1 zinc finger protein, zinc finger protein 1, ZNF475 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZFP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- transcription regulator
- double-stranded DNA binding
- Zinc-finger double domain
- protein binding
- KRAB (Kruppel-associated box) domain -A box
- sequence-specific DNA binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZFP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding
- sequence-specific DNA binding RNA polymerase II transcription factor activity