WASHC3 Gene Summary [Human]
Predicted to be involved in actin filament polymerization and exocytosis. Part of WASH complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | WASHC3 |
| Official Name | WASH complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:24256] |
| Ensembl ID | ENSG00000120860 |
| Bio databases IDs | |
| Aliases | WASH complex subunit 3 |
| Synonyms | 2900091E11RIK, 5730495F03Rik, AD016, CCD53, CCDC53, CGI-116, RGD1563761, WASH complex subunit 3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human WASHC3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Subunit CCDC53 of WASH complex
- helical domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human WASHC3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- actin filament polymerization
- endosomal transport
- exocytosis
- regulation of Arp2/3 complex-mediated actin nucleation
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- WASH complex
Molecular Function
What the gene product does at the molecular level
- protein binding