SRL Gene Summary [Human]

Predicted to enable GTP binding activity. Predicted to be involved in endocytosis and endosomal transport. Predicted to act upstream of or within response to muscle activity involved in regulation of muscle adaptation and store-operated calcium entry. Predicted to be located in sarcoplasmic reticulum lumen and sarcoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
SRL
Official Name
sarcalumenin [Source:HGNC Symbol;Acc:HGNC:11295]
Ensembl ID
ENSG00000185739
Bio databases IDs NCBI: 6345 Ensembl: ENSG00000185739
Aliases sarcalumenin
Synonyms 9830004M20Rik, SAR, Sarcalumenin
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SRL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 50S ribosome-binding GTPase
  • protein binding
  • N-terminal EH-domain containing protein
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • Dynamin family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
regulated by
regulates
role in cell
  • contraction
  • abnormal morphology
  • ultrastructure
  • relaxation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • sarcoplasmic reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SRL gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • sarcoplasmic reticulum lumen
  • sarcoplasmic reticulum membrane

Molecular Function

What the gene product does at the molecular level
  • GTP binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.