PNLIPRP1 Gene Summary [Human]
Predicted to enable calcium ion binding activity. Predicted to be involved in lipid catabolic process. Predicted to be located in extracellular region. Biomarker of prostate cancer. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | PNLIPRP1 |
| Official Name | pancreatic lipase related protein 1 [Source:HGNC Symbol;Acc:HGNC:9156] |
| Ensembl ID | ENSG00000187021 |
| Bio databases IDs | |
| Aliases | pancreatic lipase related protein 1 |
| Synonyms | pancreatic lipase-related protein 1, PLRP1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PNLIPRP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alpha/beta hydrolases
- lipase
- PLAT
- calcium ion binding
- enzyme
- protein binding
- lipoprotein lipase
- Lipoxygenase homology 2 (beta barrel) domain
- triacylglycerol lipase
Pathways
Biological processes and signaling networks where the PNLIPRP1 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PNLIPRP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lipid metabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- triglyceride lipase activity
- lipase activity