Pnliprp1 Gene Summary [Rat]

Enables lipase activity. Involved in pancreas development; response to glucocorticoid; and response to peptide hormone. Located in extracellular space. Orthologous to human PNLIPRP1 (pancreatic lipase related protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pnliprp1
Official Name
pancreatic lipase-related protein 1 [Source:RGD Symbol;Acc:620792]
Ensembl ID
ENSRNOG00000017908
Bio databases IDs NCBI: 84028 Ensembl: ENSRNOG00000017908
Aliases pancreatic lipase-related protein 1
Synonyms pancreatic lipase-related protein 1, PLRP1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pnliprp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • alpha/beta hydrolases
  • lipase
  • PLAT
  • calcium ion binding
  • enzyme
  • protein binding
  • lipoprotein lipase
  • Lipoxygenase homology 2 (beta barrel) domain
  • triacylglycerol lipase

Pathways

Biological processes and signaling networks where the Pnliprp1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • glaucoma
  • weight gain
  • insulin resistance
  • obesity
  • autoimmune pancreatitis
regulated by
regulates
  • enzyme
role in cell
  • size

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Pnliprp1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • lipid metabolic process

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • calcium ion binding
  • triglyceride lipase activity
  • lipase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.