TMPPE Gene Summary [Human]
Predicted to enable hydrolase activity and metal ion binding activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMPPE |
| Official Name | transmembrane protein with metallophosphoesterase domain [Source:HGNC Symbol;Acc:HGNC:33865] |
| Ensembl ID | ENSG00000188167 |
| Bio databases IDs | |
| Aliases | transmembrane protein with metallophosphoesterase domain |
| Synonyms | transmembrane protein with metallophosphoesterase domain |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMPPE often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- metallophosphatase superfamily, metallophosphatase domain
- Calcineurin-like phosphoesterase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMPPE gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- hydrolase activity