DYNLT4 Gene Summary [Human]

Enables protein phosphatase 1 binding activity. Predicted to be involved in microtubule-based movement. Located in acrosomal vesicle; cytoskeleton; and sperm flagellum. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
DYNLT4
Official Name
dynein light chain Tctex-type 4 [Source:HGNC Symbol;Acc:HGNC:32315]
Ensembl ID
ENSG00000188396
Bio databases IDs NCBI: 343521 Ensembl: ENSG00000188396
Aliases dynein light chain Tctex-type 4, novel Tctex-1 family domain-containing protein
Synonyms 4833401D15Rik, dynein light chain Tctex-type 4, LOC102551208, N22.1, TCTEX1D4, TCTEX2 beta, TCTEX2 β
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DYNLT4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Tctex-1 family
  • protein phosphatase 1 binding
  • dynein light chain (DLC)-like domain superfamily
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular membrane-bounded organelle
  • Nucleus
  • vesicles
  • microtubules
  • axonemes
  • microtubule organizing centers
  • nucleoli
  • sperm tail
  • acrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human DYNLT4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • microtubule-based movement

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasmic dynein complex
  • microtubule organizing center
  • cytoplasm
  • acrosomal vesicle
  • intracellular membrane-bounded organelle
  • nucleolus
  • sperm flagellum
  • axoneme

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • protein phosphatase 1 binding
  • dynein intermediate chain binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.