OTUD6A Gene Summary [Human]
Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA2 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]
Details
| Type | Protein Coding |
| Official Symbol | OTUD6A |
| Official Name | OTU deubiquitinase 6A [Source:HGNC Symbol;Acc:HGNC:32312] |
| Ensembl ID | ENSG00000189401 |
| Bio databases IDs | |
| Aliases | OTU deubiquitinase 6A |
| Synonyms | DUBA2, EG408193, HSHIN6, OTU deubiquitinase 6A, OTU domain containing 6A, RGD1560855 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human OTUD6A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- peptidase
- ubiquitin-specific protease
- protein binding
- OTU-like cysteine protease
- OTU (ovarian tumor) domain family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human OTUD6A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein K11-linked deubiquitination
- proteolysis
- protein K29-linked deubiquitination
Molecular Function
What the gene product does at the molecular level
- ubiquitin-specific protease activity
- protein binding