FUT11 Gene Summary [Human]

Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to be located in Golgi cisterna membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
FUT11
Official Name
fucosyltransferase 11 [Source:HGNC Symbol;Acc:HGNC:19233]
Ensembl ID
ENSG00000196968
Bio databases IDs NCBI: 170384 Ensembl: ENSG00000196968
Aliases fucosyltransferase 11, alpha (1,3) fucosyltransferase
Synonyms 3110009G03Rik, AI317183, fucosyltransferase 11, FUCTXI
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FUT11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • peptide-O-fucosyltransferase
  • Fucosyltransferase, N-terminal
  • fucosyltransferase
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • pancreatic cancer
  • organismal death
  • asthma
  • preeclampsia
regulated by
role in cell
  • migration
  • growth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Endoplasmic Reticulum
  • endoplasmic reticulum membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human FUT11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • fucosylation
  • protein glycosylation

Cellular Component

Where in the cell the gene product is active
  • Golgi cisterna membrane
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • alpha-(1->3)-fucosyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.