Fut11 Gene Summary [Mouse]
Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in N-glycan fucosylation and protein O-linked fucosylation. Predicted to be located in Golgi cisterna membrane and Golgi membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human FUT11 (fucosyltransferase 11). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fut11 |
| Official Name | fucosyltransferase 11 [Source:MGI Symbol;Acc:MGI:1920318] |
| Ensembl ID | ENSMUSG00000039357 |
| Bio databases IDs | |
| Aliases | fucosyltransferase 11 |
| Synonyms | 3110009G03Rik, AI317183, fucosyltransferase 11, FUCTXI |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fut11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- peptide-O-fucosyltransferase
- Fucosyltransferase, N-terminal
- fucosyltransferase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fut11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fucosylation
- protein glycosylation
Cellular Component
Where in the cell the gene product is active
- Golgi cisterna membrane
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- alpha-(1->3)-fucosyltransferase activity