ANKRD13B Gene Summary [Human]
Enables ubiquitin-dependent protein binding activity. Involved in negative regulation of receptor internalization. Located in endosome; perinuclear region of cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ANKRD13B |
| Official Name | ankyrin repeat domain 13B [Source:HGNC Symbol;Acc:HGNC:26363] |
| Ensembl ID | ENSG00000198720 |
| Bio databases IDs | |
| Aliases | ankyrin repeat domain 13B |
| Synonyms | ankyrin repeat domain 13B, B930093C12RIK, FLJ25555, RGD1564005 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ANKRD13B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ankyrin repeats (many copies)
- protein binding activity, bridging
- Ankyrin repeats (3 copies)
- GPCR-chaperone
- ankyrin repeats
- Ankyrin repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- intracellular membrane-bounded organelle
- Cytoplasm
- perinuclear region
- early endosomes
- late endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ANKRD13B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of receptor internalization
Cellular Component
Where in the cell the gene product is active
- early endosome
- perinuclear region of cytoplasm
- cytoplasm
- intracellular membrane-bounded organelle
- late endosome
- plasma membrane