BOD1L1 Gene Summary [Human]

Predicted to enable protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Involved in cellular response to DNA damage stimulus and replication fork processing. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
BOD1L1
Official Name
biorientation of chromosomes in cell division 1 like 1 [Source:HGNC Symbol;Acc:HGNC:31792]
Ensembl ID
ENSG00000038219
Bio databases IDs NCBI: 259282 Ensembl: ENSG00000038219
Aliases biorientation of chromosomes in cell division 1 like 1
Synonyms A230054D04Rik, Abp-10, AF013969, biorientation of chromosomes in cell division 1-like, biorientation of chromosomes in cell division 1-like 1, BOD1L, FAM44A, KIAA1327, mKIAA1327
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human BOD1L1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RecF/RecN/SMC N terminal domain
  • COMPASS (Complex proteins associated with Set1p) component shg1
  • Synaptonemal complex protein 1 (SCP-1)
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • metabolic syndrome X
regulated by
  • hydrogen peroxide
  • RHOJ
  • alpha-tocopherol
  • adavosertib
role in cell
  • processing
  • DNA damage response

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human BOD1L1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • DNA repair
  • replication fork processing
  • response to DNA damage stimulus

Cellular Component

Where in the cell the gene product is active
  • Set1C/COMPASS complex
  • chromosome
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.