ZNF358 Gene Summary [Human]
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic forelimb morphogenesis; neural tube development; and stem cell population maintenance. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZNF358 |
| Official Name | zinc finger protein 358 [Source:HGNC Symbol;Acc:HGNC:16838] |
| Ensembl ID | ENSG00000198816 |
| Bio databases IDs | |
| Aliases | zinc finger protein 358 |
| Synonyms | ZFEND, Zfp358, zinc finger protein 358 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF358 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- zinc finger
- transcription regulator
- Drought induced 19 protein (Di19), zinc-binding
- C2H2-type zinc-finger domain
- Zinc-finger double domain
- SprT-like zinc ribbon domain
- C2H2-type zinc finger
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZNF358 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neural tube development
- stem cell maintenance
- embryonic forelimb morphogenesis
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- sequence-specific DNA binding transcription factor activity
- metal ion binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding