ECT2L Gene Summary [Human]
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ECT2L |
| Official Name | epithelial cell transforming 2 like [Source:HGNC Symbol;Acc:HGNC:21118] |
| Ensembl ID | ENSG00000203734 |
| Bio databases IDs | |
| Aliases | epithelial cell transforming 2 like, lung specific F-box and DH domain containing protein, F-box protein 49 |
| Synonyms | ARHGEF32, C330021H03Rik, C6orf91, dJ509I19.2, dJ509I19.3, dJ509I19.5, epithelial cell transforming 2 like, epithelial cell transforming sequence 2 oncogene-like, FBXO49, Gm10331, LFDH |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ECT2L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- F-box domain
- RhoGEF
- F-box domain superfamily
- F-box-like
- Pleckstrin homology-like domain
- DD_R_PKA_DPY30-like
- Domain of unknown function (DUF4347)
- RhoGEF domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ECT2L gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- guanyl-nucleotide exchange factor activity