LY6G6C Gene Summary [Human]

LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]

Details

Type
Protein Coding
Official Symbol
LY6G6C
Official Name
lymphocyte antigen 6 family member G6C [Source:HGNC Symbol;Acc:HGNC:13936]
Ensembl ID
ENSG00000204421
Bio databases IDs NCBI: 80740 Ensembl: ENSG00000204421
Aliases lymphocyte antigen 6 family member G6C
Synonyms 1110003M04Rik, C6orf24, G6c, lymphocyte antigen 6 family member G6C, NG24
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LY6G6C often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • TFP
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Plasma Membrane
  • plasma membrane extracellular face

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human LY6G6C gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • external side of plasma membrane
  • macromolecular complex
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.