CYS1 Gene Summary [Human]
Predicted to enable chromatin binding activity and transcription corepressor activity. Predicted to act upstream of or within animal organ development and regulation of transcription, DNA-templated. Predicted to be located in cytoskeleton; membrane raft; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CYS1 |
| Official Name | cystin 1 [Source:HGNC Symbol;Acc:HGNC:18525] |
| Ensembl ID | ENSG00000205795 |
| Bio databases IDs | |
| Aliases | cystin 1 |
| Synonyms | 2900006B19Rik, CCAP, Cilia-Associated, ck, CPK, CYSTIN, cystin 1, LOC686584 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CYS1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- transcription co-repressor
- chromatin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic obstructive pulmonary disease
- chronic bronchitis
- gout
- polycystic kidney disease
- autosomal recessive polycystic kidney disease
role in cell
- expression in
- ubiquitination in
- architecture
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- cell surface
- cellular membrane
- Nucleus
- basal bodies
- axonemes
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CYS1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cilium
- cytosol
- cilium membrane
Molecular Function
What the gene product does at the molecular level
- protein binding