COPG2 Gene Summary [Human]
Predicted to enable structural molecule activity. Involved in intra-Golgi vesicle-mediated transport. Part of COPI vesicle coat. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | COPG2 |
| Official Name | COPI coat complex subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:2237] |
| Ensembl ID | ENSG00000158623 |
| Bio databases IDs | |
| Aliases | COPI coat complex subunit gamma 2, coat protein, nonclathrin, gamma-2-cop |
| Synonyms | 2-COP, coatomer protein complex, subunit gamma 2, coatomer protein complex, subunit γ 2, COPI coat complex subunit gamma 2, COPI coat complex subunit γ 2, gamma-2-COP, RGD1566215, γ-2-COP |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human COPG2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Myosin-binding striated muscle assembly central
- Coatomer gamma subunit appendage platform subdomain
- Coatomer subunit gamma-1 C-terminal appendage platform
- Adaptin N terminal region
- HEAT repeats
- transporter
Pathways
Biological processes and signaling networks where the COPG2 gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- cytosol
- endoplasmic reticulum membrane
- Golgi membrane
- growth cone
- transport vesicles
- trans Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human COPG2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- organelle transport along microtubule
- ER to Golgi vesicle-mediated transport
- retrograde vesicle-mediated transport, Golgi to ER
- intra-Golgi vesicle-mediated transport
- intracellular protein transport
- protein secretion
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- growth cone
- cytosol
- Golgi membrane
- endoplasmic reticulum
- endoplasmic reticulum-Golgi intermediate compartment
- transport vesicle
- COPI vesicle coat
Molecular Function
What the gene product does at the molecular level
- structural molecule activity