HBM Gene Summary [Human]
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. This gene has an ORF encoding a 141 aa polypeptide which is similar to the delta globins found in reptiles and birds. This locus was originally described as a pseudogene; however, it is currently thought to be a protein-coding gene. [provided by RefSeq, Jul 2008]
Details
| Type | Processed Transcript |
| Official Symbol | HBM |
| Official Name | hemoglobin subunit mu [Source:HGNC Symbol;Acc:HGNC:4826] |
| Ensembl ID | ENSG00000206177 |
| Bio databases IDs | |
| Aliases | hemoglobin subunit mu |
| Synonyms | haemoglobin subunit mu, HBAP2, HBK, hemoglobin subunit mu |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HBM often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Globin
- Globin-like protein superfamily
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human HBM gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- oxygen transport
- hydrogen peroxide catabolic process
Cellular Component
Where in the cell the gene product is active
- hemoglobin complex
- haptoglobin-hemoglobin complex
Molecular Function
What the gene product does at the molecular level
- peroxidase activity
- oxygen binding
- protein binding
- metal ion binding
- organic acid binding
- oxygen transporter activity
- haptoglobin binding
- heme binding