MAP10 Gene Summary [Human]
Enables microtubule binding activity. Involved in microtubule cytoskeleton organization; positive regulation of cytokinesis; and regulation of microtubule-based process. Located in microtubule cytoskeleton and midbody. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MAP10 |
| Official Name | microtubule associated protein 10 [Source:HGNC Symbol;Acc:HGNC:29265] |
| Ensembl ID | ENSG00000212916 |
| Bio databases IDs | |
| Aliases | microtubule associated protein 10, microtubule regulator 120 KDa |
| Synonyms | 4933403G14Rik, KIAA1383, microtubule-associated protein 10, mKIAA1383, MTR120, RGD1308644 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MAP10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- domain of unknown function
- Protein of unknown function (DUF4497)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- centrosome
- midbody
- spindle pole
- cytoplasmic microtubule
- central spindle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MAP10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- spindle midzone assembly involved in mitosis
- cytoplasmic microtubule organization
- positive regulation of cytokinesis
- regulation of microtubule-based process
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoplasmic microtubule
- midbody
Molecular Function
What the gene product does at the molecular level
- microtubule binding