ZC3H18 Gene Summary [Human]
Enables mRNA cap binding complex binding activity and protein-macromolecule adaptor activity. Involved in RNA destabilization. Located in nuclear speck. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZC3H18 |
| Official Name | zinc finger CCCH-type containing 18 [Source:HGNC Symbol;Acc:HGNC:25091] |
| Ensembl ID | ENSG00000158545 |
| Bio databases IDs | |
| Aliases | zinc finger CCCH-type containing 18 |
| Synonyms | 1190001B23Rik, 5830416A07Rik, NHN1, zinc finger CCCH-type containing 18 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZC3H18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc finger
- RNA-binding, Nab2-type zinc finger
- binding protein
- CCCH-type zinc finger
- protein binding activity, bridging
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- protein binding
- zinc finger domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZC3H18 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA destabilization
Cellular Component
Where in the cell the gene product is active
- nuclear speck
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- metal ion binding
- protein binding, bridging