PTPRCAP Gene Summary [Human]
The protein encoded by this gene was identified as a transmembrane phosphoprotein specifically associated with tyrosine phosphatase PTPRC/CD45, a key regulator of T- and B-lymphocyte activation. The interaction with PTPRC may be required for the stable expression of this protein. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | PTPRCAP |
| Official Name | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] |
| Ensembl ID | ENSG00000213402 |
| Bio databases IDs | |
| Aliases | protein tyrosine phosphatase receptor type C associated protein |
| Synonyms | CD-45-AP, LPAP, LSM-1, protein tyrosine phosphatase receptor type C associated protein, protein tyrosine phosphatase, receptor type, C-associated protein, protein tyrosine phosphatase receptor type C polypeptide-associated protein |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PTPRCAP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein tyrosine phosphatase receptor type C-associated
- extracellular domain
- transmembrane domain
- protein binding
- acidic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- androgenic alopecia
- lymphoid hyperplasia
role in cell
- quantity
- apoptosis
- proliferation
- survival
- killing
- function
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PTPRCAP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding