HEPN1 Gene Summary [Human]
This gene is expressed predominantly in the liver. Transient transfection studies show the expression of this gene significantly inhibits cell growth, suggesting a role for this gene in apoptosis. Expression of this gene is down-regulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). This gene maps to the 3'-noncoding region of the HEPACAM gene (GeneID:220296) on the antisense strand. [provided by RefSeq, Aug 2020]
Details
| Type | Protein Coding |
| Official Symbol | HEPN1 |
| Official Name | hepatocellular carcinoma, down-regulated 1 [Source:HGNC Symbol;Acc:HGNC:34400] |
| Ensembl ID | ENSG00000221932 |
| Bio databases IDs | |
| Aliases | hepatocellular carcinoma, down-regulated 1, cancer susceptibility gene HEPN1 |
| Synonyms | hepatocellular carcinoma, down-regulated 1 |
| Species | Human, Homo sapiens |
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown