PCGEM1 Gene Summary [Human]
This gene produces a long non-coding RNA that is overexpressed in prostate cancer and may act a marker for tumor progression. This RNA may act a negative regulator of apoptosis, and may promote activity of androgen receptor and Myc. [provided by RefSeq, Dec 2017]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | PCGEM1 |
| Official Name | PCGEM1 prostate-specific transcript [Source:HGNC Symbol;Acc:HGNC:30145] |
| Ensembl ID | ENSG00000227418 |
| Bio databases IDs | |
| Aliases | PCGEM1 prostate-specific transcript, non-protein coding RNA 71, long intergenic non-protein coding RNA 71, prostate cancer associated transcript 9, prostate cancer gene expression marker 1 |
| Synonyms | LINC00071, NCRNA00071, PCAT9, PCGEM1 prostate-specific transcript |
| Species | Human, Homo sapiens |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- epithelial cancer
- gastric epithelial cancer
- prostate cancer
- prostatic carcinoma
- gastric carcinoma
regulated by
- mir-145
- MEF2
role in cell
- proliferation
- expression in
- apoptosis
- invasion by
- activation in
- migration
- glycolysis in
- recruitment in
- generation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PCGEM1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of apoptotic process