TUBA4B Gene Summary [Human]

Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be active in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
TUBA4B
Official Name
tubulin alpha 4b [Source:HGNC Symbol;Acc:HGNC:18637]
Ensembl ID
ENSG00000243910
Bio databases IDs NCBI: 80086 Ensembl: ENSG00000243910
Aliases tubulin alpha 4b
Synonyms alpha TUBULIN CHAIN4, TUBA4, tubulin alpha 4b, tubulin α 4b, α TUBULIN CHAIN4
Species
Human, Homo sapiens

Pathways

Biological processes and signaling networks where the TUBA4B gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic juvenile idiopathic arthritis
regulated by
  • PC-SPES
  • SALL4
  • megakaryocytes

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TUBA4B gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • microtubule cytoskeleton organization
  • mitotic cell cycle

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • metal ion binding
  • structural constituent of cytoskeleton
  • hydrolase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.