PMF1-BGLAP Gene Summary [Human]
This locus represents naturally occurring read-through transcription between the neighboring PMF1 (polyamine-modulated factor 1) and BGLAP (bone gamma-carboxyglutamate Gla protein) genes on chromosome 1. Alternative splicing results in multiple transcript variants encoding isoforms that share sequence identity with the upstream gene product, but they contain distinct C-termini due to frameshifts versus the downstream gene coding sequence. [provided by RefSeq, Dec 2010]
Details
| Type | Protein Coding |
| Official Symbol | PMF1-BGLAP |
| Official Name | PMF1-BGLAP readthrough [Source:HGNC Symbol;Acc:HGNC:42953] |
| Ensembl ID | ENSG00000260238 |
| Bio databases IDs | |
| Aliases | PMF1-BGLAP readthrough |
| Synonyms | PMF-1, PMF1-BGLAP readthrough |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PMF1-BGLAP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nnf1
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown