CWC25 Gene Summary [Human]

This gene encodes a factor that is part of the multi-protein C complex involved in pre-mRNA splicing. Alternatively spliced transcripts have been described for this gene. [provided by RefSeq, Nov 2012]

Details

Type
Protein Coding
Official Symbol
CWC25
Official Name
CWC25 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:25989]
Ensembl ID
ENSG00000273559
Bio databases IDs NCBI: 54883 Ensembl: ENSG00000273559
Aliases CWC25 spliceosome associated protein homolog
Synonyms 1300013D05RIK, CCDC49, CWC25 spliceosome-associated protein, CWC25 spliceosome-associated protein homolog, R75228, RGD1305258
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CWC25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Pre-mRNA splicing factor
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • major depression
regulated by
  • DAP3
  • dopamine
  • beta-estradiol
role in cell
  • splicing by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • spliceosomes
  • nucleoplasm
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CWC25 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nuclear mRNA splicing, via spliceosome

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear speck
  • U2-type catalytic step 1 spliceosome
  • U2-type spliceosomal complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.