Cwc25 Gene Summary [Mouse]
Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nuclear speck. Predicted to be part of U2-type catalytic step 1 spliceosome. Is expressed in dermis and epidermis. Orthologous to human CWC25 (CWC25 spliceosome associated protein homolog). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Cwc25 |
| Official Name | CWC25 spliceosome-associated protein [Source:MGI Symbol;Acc:MGI:1914730] |
| Ensembl ID | ENSMUSG00000018541 |
| Bio databases IDs | |
| Aliases | CWC25 spliceosome-associated protein |
| Synonyms | 1300013D05RIK, CCDC49, CWC25 spliceosome-associated protein, CWC25 spliceosome-associated protein homolog, R75228, RGD1305258 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cwc25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Pre-mRNA splicing factor
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cwc25 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- U2-type catalytic step 1 spliceosome
- U2-type spliceosomal complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding