Rpl13 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in bone development. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; cerebral cortex ventricular layer; cortical plate; and retina. Orthologous to human RPL13 (ribosomal protein L13). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl13 |
| Official Name | ribosomal protein L13 [Source:MGI Symbol;Acc:MGI:105922] |
| Ensembl ID | ENSMUSG00000000740 |
| Bio databases IDs | |
| Aliases | ribosomal protein L13 |
| Synonyms | A52, BBC1, D16S444E, D16S44E, eL13, L13, ribosomal protein L13, SEMDIST |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- protein binding
- Ribosomal protein L13e
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl13 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- Isidor-Toutain type spondyloepimetaphyseal dysplasia
- myelodysplastic syndrome
- Parkinson disease
- bipolar disorder
- lymphomagenesis
- lymphoma
regulated by
- LH
- AKT
- MYCL
- trichostatin A
- PDGF-BB
- CD 437
- elastase
- torin1
- PknG
- tretinoin
regulates
- mutT3
role in cell
- cell death
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- pH resistant lipid raft fraction
- detergent resistant lipid raft fraction
- ribosome
- Endoplasmic Reticulum
- cytosol
- nucleoli
- nuclear envelope
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- blastocyst development
- bone development
- translation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosolic ribosome
- cytoplasm
- membrane
- cytosol
- endoplasmic reticulum
- synapse
- cytosolic large ribosomal subunit
- nucleolus
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome