Plin4 Gene Summary [Mouse]

Located in plasma membrane. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; immune system; and nervous system. Orthologous to human PLIN4 (perilipin 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Plin4
Official Name
perilipin 4 [Source:MGI Symbol;Acc:MGI:1929709]
Ensembl ID
ENSMUSG00000002831
Bio databases IDs NCBI: 57435 Ensembl: ENSMUSG00000002831
Aliases perilipin 4
Synonyms KIAA1881, MDRV, MGI:1929709, mKIAA1881, MRUPAV, NIPA2, perilipin 4, S3-12, VACUOLAR NEUROMYOPATHY
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Plin4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Perilipin family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colorectal cancer
  • glioblastoma
  • glioblastoma cancer
  • osteoarthritis
  • autosomal dominant muscular dystrophy with rimmed vacuoles
  • doxorubicin induced cardiotoxicity
regulated by
  • lipopolysaccharide
  • troglitazone
  • insulin
  • MAPT
  • pirinixic acid
  • Immunoglobulin
  • nelfinavir
  • RYR1
  • EIF2S1
  • cisplatin

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane
  • lipid droplets
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Plin4 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • lipid particle
  • cytosol
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.