PLIN4 Gene Summary [Human]
Members of the perilipin family, such as PLIN4, coat intracellular lipid storage droplets (Wolins et al., 2003 [PubMed 12840023]).[supplied by OMIM, Feb 2010]
Details
| Type | Protein Coding |
| Official Symbol | PLIN4 |
| Official Name | perilipin 4 [Source:HGNC Symbol;Acc:HGNC:29393] |
| Ensembl ID | ENSG00000167676 |
| Bio databases IDs | |
| Aliases | perilipin 4 |
| Synonyms | KIAA1881, MDRV, MGI:1929709, mKIAA1881, MRUPAV, NIPA2, perilipin 4, S3-12, VACUOLAR NEUROMYOPATHY |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PLIN4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Perilipin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colorectal cancer
- glioblastoma
- glioblastoma cancer
- osteoarthritis
- autosomal dominant muscular dystrophy with rimmed vacuoles
- doxorubicin induced cardiotoxicity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- lipid droplets
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PLIN4 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- lipid particle
- cytosol
- plasma membrane