Tmem39a Gene Summary [Mouse]
Predicted to be involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of viral genome replication. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human TMEM39A (transmembrane protein 39A). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem39a |
| Official Name | transmembrane protein 39a [Source:MGI Symbol;Acc:MGI:1915096] |
| Ensembl ID | ENSMUSG00000002845 |
| Bio databases IDs | |
| Aliases | transmembrane protein 39a |
| Synonyms | 2610033C09Rik, RGD1306421, SUSR2, transmembrane protein 39A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem39a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Putative transmembrane protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem39a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagy
- positive regulation of viral genome replication
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- protein binding