Ccpg1 Gene Summary [Mouse]
Acts upstream of or within positive regulation of transcription by RNA polymerase II and regulation of Rho guanyl-nucleotide exchange factor activity. Located in membrane. Is expressed in cranial ganglion; dorsal root ganglion; sensory organ; and skeleton. Orthologous to human CCPG1 (cell cycle progression 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccpg1 |
| Official Name | cell cycle progression 1 [Source:MGI Symbol;Acc:MGI:1196419] |
| Ensembl ID | ENSMUSG00000034563 |
| Bio databases IDs | |
| Aliases | cell cycle progression 1 |
| Synonyms | 1700030B06Rik, 1810073J13Rik, 9430028F23Rik, AI426686, cell cycle progression 1, Cell cycle progression 8, CPR8, D9Ertd392e |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccpg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- early infantile epileptic encephalopathy type 80
role in cell
- proliferation
- expression in
- cell cycle progression
- transcription in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccpg1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of cell proliferation
- positive regulation of cell cycle
- regulation of Rho guanyl-nucleotide exchange factor activity
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding