Slc47a1 Gene Summary [Mouse]
Enables polyspecific organic cation:proton antiporter activity. Involved in monoatomic cation transmembrane transport and xenobiotic transmembrane transport. Located in plasma membrane. Is expressed in several structures, including liver; lung; metanephros; nervous system; and spleen. Orthologous to several human genes including SLC47A1 (solute carrier family 47 member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc47a1 |
| Official Name | solute carrier family 47, member 1 [Source:MGI Symbol;Acc:MGI:1914723] |
| Ensembl ID | ENSMUSG00000010122 |
| Bio databases IDs | |
| Aliases | solute carrier family 47, member 1 |
| Synonyms | 1300013J15Rik, MATE1, mMATE1, RGD1311123, solute carrier family 47 member 1, solute carrier family 47, member 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc47a1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- hydrogen ion transporter
- MatE
- amide transporter
- L-amino acid transporter
- basic amino acid transporter
- putative efflux protein, MATE family
- organic cation transporter
- Multidrug and toxic compound extrusion family and similar proteins
- xenobiotic transporter
- antiporter
- thiamin transporter
- transporter
- putrescine transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- vesicles
- apical membrane
- basolateral membrane