Stard3nl Gene Summary [Mouse]
Predicted to enable cholesterol binding activity and protein homodimerization activity. Predicted to be involved in cholesterol transport and vesicle tethering to endoplasmic reticulum. Predicted to be located in endosome and organelle membrane contact site. Predicted to be active in endoplasmic reticulum-endosome membrane contact site and late endosome membrane. Predicted to colocalize with endoplasmic reticulum membrane. Is expressed in respiratory system cartilage; sensory organ; skeleton; and tarsus. Orthologous to human STARD3NL (STARD3 N-terminal like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Stard3nl |
| Official Name | STARD3 N-terminal like [Source:MGI Symbol;Acc:MGI:1923455] |
| Ensembl ID | ENSMUSG00000003062 |
| Bio databases IDs | |
| Aliases | STARD3 N-terminal like |
| Synonyms | 0610035N01Rik, 6530409L22RIK, LOC102557384, MENTHO, STARD3 N-terminal like |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Stard3nl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cholesterol binding
- Cholesterol-capturing domain
- protein homodimerization
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- cellular membrane
- endosomes
- lysosome
- cytosol
- endoplasmic reticulum membrane
- endosomal membrane
- early endosomes
- organelle membrane contact site
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Stard3nl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cholesterol transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- late endosome membrane
- endosome
- intracellular membrane-bounded organelle
- organelle membrane contact site
- membrane
- cytosol
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein homodimerization activity
- protein binding
- cholesterol binding