Yju2 Gene Summary [Mouse]
Predicted to enable metal ion binding activity. Predicted to be involved in RNA splicing and negative regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to be part of U2-type catalytic step 1 spliceosome. Is expressed in several structures, including aorta; endocrine gland; genitourinary system; nervous system; and trachea. Orthologous to human YJU2 (YJU2 splicing factor homolog). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Yju2 |
| Official Name | YJU2 splicing factor [Source:MGI Symbol;Acc:MGI:1920136] |
| Ensembl ID | ENSMUSG00000003208 |
| Bio databases IDs | |
| Aliases | YJU2 splicing factor |
| Synonyms | 2900016D05Rik, CCDC94, YJU2 splicing factor, YJU2 splicing factor homolog |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Yju2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Saf4/Yju2 protein
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Yju2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of DNA damage response, signal transduction by p53 class mediator
- RNA splicing
- generation of catalytic spliceosome for first transesterification step
Cellular Component
Where in the cell the gene product is active
- U2-type catalytic step 1 spliceosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding