Med29 Gene Summary [Mouse]
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of core mediator complex and mediator complex. Is expressed in tibialis anterior. Orthologous to human MED29 (mediator complex subunit 29). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Med29 |
| Official Name | mediator complex subunit 29 [Source:MGI Symbol;Acc:MGI:1914474] |
| Ensembl ID | ENSMUSG00000003444 |
| Bio databases IDs | |
| Aliases | mediator complex subunit 29 |
| Synonyms | 2810405O22RIK, AU020902, Intersex, IXL, MED2, mediator complex subunit 29, RGD1311009 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Med29 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Mediator complex subunit 29
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Med29 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription elongation from RNA polymerase II promoter
- RNA polymerase II transcriptional preinitiation complex assembly
- positive regulation of transcription initiation from RNA polymerase II promoter
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- core mediator complex
- mediator complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- transcription cofactor activity
- protein binding
- transcription factor binding