Pcp2 Gene Summary [Mouse]
Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within G protein-coupled opsin signaling pathway. Is expressed in central nervous system and retina. Orthologous to human PCP2 (Purkinje cell protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pcp2 |
| Official Name | Purkinje cell protein 2 (L7) [Source:MGI Symbol;Acc:MGI:97508] |
| Ensembl ID | ENSMUSG00000004630 |
| Bio databases IDs | |
| Aliases | Purkinje cell protein 2 (L7) |
| Synonyms | GPSM4, L7, MGC41903, PCD5, Purkinje cell protein 2, Purkinje cell protein 2 (L7) |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein regulatory motif
- guanyl-nucleotide exchange factor
- GoLoco motif
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcp2 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- protein binding
- guanyl-nucleotide exchange factor activity