Slbp Gene Summary [Mouse]
Enables histone pre-mRNA stem-loop binding activity and mRNA binding activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Located in cytoplasm and nucleus. Part of histone pre-mRNA 3'end processing complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; hemolymphoid system gland; and pancreas. Orthologous to human SLBP (stem-loop histone mRNA binding protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slbp |
| Official Name | stem-loop binding protein [Source:MGI Symbol;Acc:MGI:108402] |
| Ensembl ID | ENSMUSG00000004642 |
| Bio databases IDs | |
| Aliases | stem-loop binding protein |
| Synonyms | HBP, LOC682588, stem-loop binding protein, stem-loop histone mRNA binding protein |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slbp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- mRNA binding
- nuclear localization sequence
- protein binding
- Histone RNA hairpin-binding protein RNA-binding domain
- identical protein binding
- translation activation domain
- RNA-binding domain
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slbp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cap-dependent translational initiation
- histone mRNA 3'-end processing
- mRNA transport
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- histone pre-mRNA 3'end processing complex
- cytosol
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- RNA binding
- protein binding
- mRNA binding
- histone pre-mRNA DCP binding
- histone pre-mRNA stem-loop binding