Slc30a4 Gene Summary [Mouse]
Enables zinc ion transmembrane transporter activity. Involved in zinc ion transmembrane transport. Acts upstream of or within zinc export across plasma membrane. Predicted to be located in endosome membrane and late endosome. Predicted to be active in plasma membrane. Is expressed in medulla oblongata basal plate mantle layer and placenta. Orthologous to human SLC30A4 (solute carrier family 30 member 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc30a4 |
| Official Name | solute carrier family 30 (zinc transporter), member 4 [Source:MGI Symbol;Acc:MGI:1345282] |
| Ensembl ID | ENSMUSG00000005802 |
| Bio databases IDs | |
| Aliases | solute carrier family 30 (zinc transporter), member 4 |
| Synonyms | lm, solute carrier family 30 member 4, solute carrier family 30 (zinc transporter), member 4, ZNT4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc30a4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cation diffusion facilitator family transporter
- protein binding
- zinc ion transporter
- Cation efflux family
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endosomal membrane fractions
- cell surface
- Plasma Membrane
- endosomes
- vesicles
- granules
- apical cytoplasm
- endosomal membrane
- late endosomes
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc30a4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to zinc ion
- zinc ion transmembrane transport
- response to toxin
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- cytoplasm
- late endosome
- endosome membrane
- plasma membrane
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- antiporter activity
- metal ion binding
- zinc ion transmembrane transporter activity