Sqor Gene Summary [Mouse]

Predicted to enable FAD binding activity; glutathione-dependent sulfide quinone oxidoreductase activity; and sulfide:quinone oxidoreductase activity. Predicted to be involved in sulfide oxidation, using sulfide:quinone oxidoreductase. Located in mitochondrial inner membrane. Orthologous to human SQOR (sulfide quinone oxidoreductase). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sqor
Official Name
sulfide quinone oxidoreductase [Source:MGI Symbol;Acc:MGI:1929899]
Ensembl ID
ENSMUSG00000005803
Bio databases IDs NCBI: 59010 Ensembl: ENSMUSG00000005803
Aliases sulfide quinone oxidoreductase
Synonyms 0610039J17Rik, 4930557M22Rik, Cc2-17, CGI-44, Flavo-binding, PRO1975, SQR, SQRDL, sulfide quinone oxidoreductase, sulphide quinone oxidoreductase
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sqor often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • sulfur group:quinone oxidoreductase
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • sulfide-quinone oxidoreductase deficiency
  • Leigh syndrome
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Mitochondria
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Sqor gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sulfide oxidation, using sulfide:quinone oxidoreductase

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • FAD binding
  • quinone binding
  • sulfide:quinone oxidoreductase activity

Gene-Specific Assays for Results You Can Trust

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