SQOR Gene Summary [Human]
The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012]
Details
| Type | Protein Coding |
| Official Symbol | SQOR |
| Official Name | sulfide quinone oxidoreductase [Source:HGNC Symbol;Acc:HGNC:20390] |
| Ensembl ID | ENSG00000137767 |
| Bio databases IDs | |
| Aliases | sulfide quinone oxidoreductase |
| Synonyms | 0610039J17Rik, 4930557M22Rik, Cc2-17, CGI-44, Flavo-binding, PRO1975, SQR, SQRDL, sulfide quinone oxidoreductase, sulphide quinone oxidoreductase |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SQOR often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- sulfur group:quinone oxidoreductase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SQOR gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sulfide oxidation, using sulfide:quinone oxidoreductase
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- FAD binding
- quinone binding
- sulfide:quinone oxidoreductase activity