Pdc Gene Summary [Mouse]
Predicted to be involved in regulation of G protein-coupled receptor signaling pathway and visual perception. Located in photoreceptor outer segment. Is expressed in several structures, including central nervous system; foot; skeleton; and spinal nerve plexus. Orthologous to human PDC (phosducin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pdc |
| Official Name | phosducin [Source:MGI Symbol;Acc:MGI:98090] |
| Ensembl ID | ENSMUSG00000006007 |
| Bio databases IDs | |
| Aliases | phosducin |
| Synonyms | 33DPTP, MEKA, PHD, PhLOP, PhLP, phosducin, Rod photoreceptor, Rpr-1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pdc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CRX binding domain
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- phospholipase inhibitor
- Phosducin
Pathways
Biological processes and signaling networks where the Pdc gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hypertension
role in cell
- action potential
- light sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- soluble fraction
- Nucleus
- cytosol
- nerve ending
- synapse
- photoreceptor outer segments
- ellipsosome
- photoreceptor inner segments
- rod outer segments
- rod inner segments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pdc gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
- regulation of G-protein coupled receptor protein signaling pathway
- visual perception
- phototransduction
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- photoreceptor inner segment
- photoreceptor outer segment
Molecular Function
What the gene product does at the molecular level
- phospholipase inhibitor activity