Prrg2 Gene Summary [Mouse]
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in blood coagulation. Predicted to be located in membrane. Predicted to be active in extracellular space and plasma membrane. Orthologous to human PRRG2 (proline rich and Gla domain 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prrg2 |
| Official Name | proline-rich Gla (G-carboxyglutamic acid) polypeptide 2 [Source:MGI Symbol;Acc:MGI:1929596] |
| Ensembl ID | ENSMUSG00000007837 |
| Bio databases IDs | |
| Aliases | proline-rich Gla (G-carboxyglutamic acid) polypeptide 2 |
| Synonyms | 1600014G02Rik, 2510041M06Rik, N4WBP1, PRGP2, proline rich and Gla domain 2, proline-rich Gla (G-carboxyglutamic acid) polypeptide 2, TMG2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prrg2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TM_EGFR-like
- protein binding
- cytosolic tail domain
- proline tyrosine motif
- Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prrg2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding