Mid1ip1 Gene Summary [Mouse]
Enables enzyme activator activity; identical protein binding activity; and ligase regulator activity. Involved in positive regulation of fatty acid biosynthetic process; positive regulation of ligase activity; and protein polymerization. Acts upstream of or within negative regulation of microtubule depolymerization. Located in cytosol; microtubule cytoskeleton; and nucleus. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; limb segment; and nervous system. Orthologous to human MID1IP1 (MID1 interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Mid1ip1 |
| Official Name | Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) [Source:MGI Symbol;Acc:MGI:1915291] |
| Ensembl ID | ENSMUSG00000008035 |
| Bio databases IDs | |
| Aliases | Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) |
| Synonyms | 3110038L01Rik, G12-like, MID1 interacting protein 1, Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)), MIG12, S14R, slap, STRAIT11499, THRSPL |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mid1ip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Thyroid hormone-inducible hepatic protein Spot 14
- protein binding
- enzyme regulator activity
- enzyme activator activity
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- infection by HIV-1
role in cell
- accumulation in
- morphology
- reverse transcription
- depolymerization
- reverse transcription in
- synthesis in
- replication in
- lipogenesis in
- growth in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- Nucleus
- microtubules
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mid1ip1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein polymerization
- regulation of lipid biosynthetic process
- lipid metabolic process
- positive regulation of ligase activity
- negative regulation of microtubule depolymerization
- positive regulation of fatty acid biosynthetic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- microtubule cytoskeleton
- cytosol
- microtubule
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding