MID1IP1 Gene Summary [Human]

Predicted to enable identical protein binding activity and protein C-terminus binding activity. Predicted to be involved in several processes, including negative regulation of microtubule depolymerization; positive regulation of fatty acid biosynthetic process; and protein polymerization. Predicted to be located in cytoplasm and microtubule cytoskeleton. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MID1IP1
Official Name
MID1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20715]
Ensembl ID
ENSG00000165175
Bio databases IDs NCBI: 58526 Ensembl: ENSG00000165175
Aliases MID1 interacting protein 1, gastrulation specific G12 homolog (zebrafish)
Synonyms 3110038L01Rik, G12-like, MID1 interacting protein 1, Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)), MIG12, S14R, slap, STRAIT11499, THRSPL
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MID1IP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Thyroid hormone-inducible hepatic protein Spot 14
  • protein binding
  • enzyme regulator activity
  • enzyme activator activity
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • infection by HIV-1
regulated by
  • dexamethasone
  • D-glucose
  • KRAS
  • ATF4
  • Jurkat E6.1 cells
  • Mef cells
  • LDLR
  • GW3965
  • carbamazepine
  • diclofenac
regulates
role in cell
  • accumulation in
  • morphology
  • reverse transcription
  • depolymerization
  • reverse transcription in
  • synthesis in
  • replication in
  • lipogenesis in
  • growth in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • microtubule cytoskeleton
  • Nucleus
  • microtubules
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MID1IP1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein polymerization
  • regulation of lipid biosynthetic process
  • lipid metabolic process
  • positive regulation of ligase activity
  • negative regulation of microtubule depolymerization
  • positive regulation of fatty acid biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • microtubule cytoskeleton
  • cytosol
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.