Snap47 Gene Summary [Mouse]
Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane and vesicle-mediated transport in synapse. Acts upstream of or within long-term synaptic potentiation. Located in dendrite; membrane; and neuronal cell body. Is active in glutamatergic synapse. Is expressed in several structures, including brain; genitourinary system; liver; pancreas; and spleen. Orthologous to human SNAP47 (synaptosome associated protein 47). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snap47 |
| Official Name | synaptosomal-associated protein, 47 [Source:MGI Symbol;Acc:MGI:1915076] |
| Ensembl ID | ENSMUSG00000009894 |
| Bio databases IDs | |
| Aliases | synaptosomal-associated protein, 47 |
| Synonyms | 1110031B06Rik, C1orf142, ESFI5812, HEL170, HEL-S-290, LOC100130093, RGD735194, SVAP1, synaptosomal-associated protein, 47, synaptosome associated protein 47 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Snap47 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Helical region found in SNAREs
- protein binding
- Pleckstrin homology-like domain
- SNARE motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- cellular membrane
- cell cortex
- synapse
- perikaryon
- dendrites
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Snap47 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- synaptic vesicle priming
- synaptic vesicle fusion to presynaptic membrane
- exocytosis
Cellular Component
Where in the cell the gene product is active
- BLOC-1 complex
- perinuclear region of cytoplasm
- endomembrane system
- SNARE complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- syntaxin binding
- SNAP receptor activity