Snap47 Gene Summary [Rat]
Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane; synaptic vesicle fusion to presynaptic active zone membrane; and synaptic vesicle priming. Predicted to act upstream of or within long-term synaptic potentiation. Is active in hippocampal mossy fiber to CA3 synapse; postsynaptic density; and presynaptic active zone. Orthologous to human SNAP47 (synaptosome associated protein 47). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snap47 |
| Official Name | synaptosome associated protein 47 [Source:RGD Symbol;Acc:735194] |
| Ensembl ID | ENSRNOG00000022472 |
| Bio databases IDs | |
| Aliases | synaptosome associated protein 47 |
| Synonyms | 1110031B06Rik, C1orf142, ESFI5812, HEL170, HEL-S-290, LOC100130093, RGD735194, SVAP1, synaptosomal-associated protein, 47, synaptosome associated protein 47 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snap47 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Helical region found in SNAREs
- protein binding
- Pleckstrin homology-like domain
- SNARE motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- cellular membrane
- cell cortex
- synapse
- perikaryon
- dendrites
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snap47 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- synaptic vesicle priming
- synaptic vesicle fusion to presynaptic membrane
- exocytosis
Cellular Component
Where in the cell the gene product is active
- BLOC-1 complex
- perinuclear region of cytoplasm
- endomembrane system
- SNARE complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- syntaxin binding
- SNAP receptor activity