Tmem86a Gene Summary [Mouse]
Enables alkenylglycerophosphocholine hydrolase activity. Predicted to be involved in lipid metabolic process. Located in endoplasmic reticulum membrane. Is expressed in several structures, including brain; gut; orbito-sphenoid; retina; and submandibular gland primordium. Orthologous to human TMEM86A (transmembrane protein 86A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem86a |
| Official Name | transmembrane protein 86A [Source:MGI Symbol;Acc:MGI:1915143] |
| Ensembl ID | ENSMUSG00000010307 |
| Bio databases IDs | |
| Aliases | transmembrane protein 86A |
| Synonyms | 1810054O13Rik, LOC105376579, RGD1305749, transmembrane protein 86A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem86a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alkenylglycerophosphocholine hydrolase
- enzyme
- protein binding
- YhhN family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem86a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lipid metabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- alkenylglycerophosphocholine hydrolase activity
- hydrolase activity